1. the process whereby a protein molecule assumes its intricate three-dimensional shape - understanding protein folding is the next step in deciphering the genetic code • Syn: protein folding • Hypernyms: organic process, biological process 2. a geological process that causes a bend in a stratum of rock • Syn: fold • Hypernyms: geological process, geologic process 3. the act of folding - he gave the napkins a double fold • Syn: fold • Derivationally related forms: fold, fold (for: fold) • Hypernyms: change of shape • Hyponyms: plication, pleating